Risk prediction of cardiovascular disease in the Asia-Pacific region: The SCORE2 Asia-Pacific model

N Abdullah; MI Abdul Jalal; ELM Barr; P Chamnan; CL Chong; L Cuenza; P Gao; I Graham; S Hilal; J Holtrop; R Jamal; TA Kalhan; H Kaneko; CH Lee; CGY Lim; X Liu; DJ Magliano; N Motamed; M Moradi-Lakeh; SK Ong; R Perera; K Prasad; JE Shaw; J De Silva; X Sim; Y Suzuki; KCB Tan; X Tang; K Venkataraman; R Wickremasinghe; H Yasunaga; F Zamani; SHJ Hageman; Z Huang; H Lee; S Kaptoge; JAN Dorresteijn; L Pennells; E Di Angelantonio; FLJ Visseren; HC Kim; S Johar; M Papadakis; A Timmis; V Aboyans; P Vardas; JW McEvoy; M Kavousi; J Ferrieres; R Huculeci; A Junia; R Krittayaphong; QN Nguyen; AH Raynaldo; A Fong; HS Kim; J Tan; I Komuro; W Almahmeed; KK Yeo; J Ako; KW Park

Journal article

Risk prediction of cardiovascular disease in the Asia-Pacific region: The SCORE2 Asia-Pacific model

N Abdullah, MI Abdul Jalal, ELM Barr, P Chamnan, CL Chong, L Cuenza, P Gao, I Graham, S Hilal, J Holtrop, R Jamal, TA Kalhan, H Kaneko, CH Lee, CGY Lim, X Liu, DJ Magliano, N Motamed, M Moradi-Lakeh, SK Ong Show all

European Heart Journal | Published : 2025

DOI: 10.1093/eurheartj/ehae609

Abstract

Background and Aims: To improve upon the estimation of 10-year cardiovascular disease (CVD) event risk for individuals without prior CVD or diabetes mellitus in the Asia-Pacific region by systematic recalibration of the SCORE2 risk algorithm. Methods: The sex-specific and competing risk-adjusted SCORE2 algorithms were systematically recalibrated to reflect CVD incidence observed in four Asia-Pacific risk regions, defined according to country-level World Health Organization age- and sex-standardized CVD mortality rates. Using the same approach as applied for the original SCORE2 models, recalibration to each risk region was completed using expected CVD incidence and risk factor distributions f..

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